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Facilitate Pharmacokinetic (PK) and Pharmacodynamic (PD) modeling and simulation with powerful tools for Nonlinear Mixed-Effects (NLME) modeling. The package provides access to the same advanced Maximum Likelihood algorithms used by the NLME-Engine in the Phoenix platform. These tools support a range of analyses, from parametric methods to individual and pooled data analysis <https://www.certara.com/app/uploads/2020/06/BR_PhoenixNLME-v4.pdf>. Execution is supported both locally or on remote machines.
| Version: | 3.0.1 |
| Depends: | R (≥ 4.0) |
| Imports: | xml2, assertthat, Certara.NLME8, data.table, jsonlite, methods, utils, ssh |
| Suggests: | rlang, knitr, rmarkdown, testthat, magrittr |
| Published: | 2024-11-20 |
| DOI: | 10.32614/CRAN.package.Certara.RsNLME |
| Author: | James Craig [aut, cre], Michael Tomashevskiy [aut], Vitalii Nazarov [aut], Shuhua Hu [ctb], Soltanshahi Fred [aut], Certara USA, Inc. [cph, fnd] |
| Maintainer: | James Craig <james.craig at certara.com> |
| License: | LGPL-3 |
| URL: | https://certara.github.io/R-RsNLME/ |
| NeedsCompilation: | no |
| Materials: | README |
| CRAN checks: | Certara.RsNLME results |
| Reference manual: | Certara.RsNLME.pdf |
| Package source: | Certara.RsNLME_3.0.1.tar.gz |
| Windows binaries: | r-devel: Certara.RsNLME_3.0.1.zip, r-release: Certara.RsNLME_3.0.1.zip, r-oldrel: Certara.RsNLME_3.0.1.zip |
| macOS binaries: | r-release (arm64): Certara.RsNLME_3.0.1.tgz, r-oldrel (arm64): Certara.RsNLME_3.0.1.tgz, r-release (x86_64): Certara.RsNLME_3.0.1.tgz, r-oldrel (x86_64): Certara.RsNLME_3.0.1.tgz |
| Reverse imports: | Certara.RsNLME.ModelBuilder |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.