influential: Identification and Classification of the Most Influential Nodes

Provides functions for the identification, classification, and ranking of influential nodes and candidate features from network and omics data. The package implements the Integrated Value of Influence (IVI) for integrative network centrality analysis, the SIR-based Influence Ranking (SIRIR) model for unsupervised influence ranking, and the Experimental data-based Integrative Ranking (ExIR) model for prioritizing candidate driver, biomarker, and mediator features from experimental omics data. Functions are provided for network reconstruction from adjacency matrices and data frames, topological analysis, centrality calculation, assessment of associations between centrality measures, and conditional probability analysis. ExIR supports bulk and single-cell omics data, including matrices, sparse matrices, data frames, tibbles, and Seurat objects.

Version:	2.3.1
Depends:	R (≥ 4.0.0)
Imports:	igraph, irlba, edgeR, cli, Matrix, SeuratObject, tibble, janitor, ranger, foreach, doParallel, ggplot2, Rcpp
LinkingTo:	Rcpp
Suggests:	Hmisc (≥ 4.3-0), mgcv (≥ 1.8-31), nortest (≥ 1.0-4), NNS (≥ 0.4.7.1), BiocManager, readr, shiny, shinythemes, shinyWidgets, shinyjs, shinycssloaders, colourpicker, magrittr, DT, knitr, rmarkdown
Published:	2026-05-28
DOI:	10.32614/CRAN.package.influential
Author:	Adrian Salavaty [aut, cre], Mirana Ramialison [ths], Peter D. Currie [ths]
Maintainer:	Adrian Salavaty <abbas.salavaty at gmail.com>
BugReports:	https://github.com/asalavaty/influential/issues
License:	GPL-3
URL:	https://github.com/asalavaty/influential, https://asalavaty.github.io/influential/
NeedsCompilation:	yes
Additional_repositories:	https://bioconductor.org/packages/release/bioc
Language:	en-US
Citation:	influential citation info
Materials:	README, NEWS
In views:	NetworkAnalysis
CRAN checks:	influential results

Documentation:

Reference manual:	influential.html , influential.pdf
Vignettes:	Introduction to influential (source, R code)

Downloads:

Package source:	influential_2.3.1.tar.gz
Windows binaries:	r-devel: influential_2.3.1.zip, r-release: influential_2.3.1.zip, r-oldrel: influential_2.3.1.zip
macOS binaries:	r-release (arm64): influential_2.3.1.tgz, r-oldrel (arm64): influential_2.3.1.tgz, r-release (x86_64): influential_2.3.1.tgz, r-oldrel (x86_64): influential_2.3.1.tgz
Old sources:	influential archive

Reverse dependencies:

Reverse imports:

networksem

Linking:

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